Optimal blood lipid levels counterbalance high polygenic risk of coronary artery disease in 130 000 individuals

Serum Lipid Levels in Children of Parents with Premature Coronary Artery Disease

The lipid factor is currently considered to be the main agent responsible for cardiovascular risk in young individuals. Several epidemiological studies have shown that atherosclerosis begins in childhood. Therefore consensus was obtained that the earlier the control begins,the better results are achieved. There are many controversies around early identification of hyperlipidemia in children . T...

Optimal blood pressure levels in patients with coronary artery disease.

ypertension is very prevalent and represents an important odifiable risk factor for coronary artery disease. Current uidelines recommend treatment of blood pressure (BP) to evels of 140/90 mm Hg, irrespective of the presence or bsence of coronary artery disease (in those without coexsting diabetes or chronic kidney disease) (1). However, few linical trials have specifically evaluated the relati...

Coronary Artery Disease Risk Factors in Patients Undergoing Coronary Artery Bypass Graft Surgery

Introduction: Nowadays, with the advancement of technology and industrial life, the prevalence of heart diseases including coronary artery diseases has considerably increased. Coronary artery diseases are one of the most common and serious diseases that threaten human life. Methods: The present study is a comparative-descriptive research. The statistical ...

Anthropometric Measures and the Risk of Coronary Artery Disease

Association of Genetic Variants Influencing Lipid Levels with Coronary Artery Disease in Japanese Individuals

BACKGROUND/OBJECTIVE In Japanese populations, we performed a replication study of genetic loci previously identified in European-descent populations as being associated with lipid levels and risk of coronary artery disease (CAD). METHODS We genotyped 48 single nucleotide polymorphisms (SNPs) from 22 candidate loci that had previously been identified by genome-wide association (GWA) meta-analy...